Research & Publications

This multicenter study from the Indian RES-Q (Registry of Stroke Care Quality) analyzes prospectively collected data from 46 stroke centers across India between 2022 and 2024 to evaluate the quality of ischemic stroke care. The study reviews demographics, clinical characteristics, treatment interventions, quality indicators, and outcomes from more than 7,000 stroke cases. As one of the first large nationwide datasets assessing stroke care quality in India, the findings provide valuable insights into current practices and emphasize the importance of continuous quality monitoring through platforms like RES-Q to standardize stroke care, reduce disparities, and improve patient outcomes across the country.

This cross-sectional study conducted at a tertiary care hospital in Uttar Pradesh, India, evaluates the role of social media in improving public awareness about stroke symptoms and risk factors. The study assessed 250 participants using a structured questionnaire to understand their knowledge of stroke warning signs, emergency response, and exposure to stroke-related information on social media platforms.

The findings reveal significant gaps in stroke awareness despite high social media usage, highlighting the untapped potential of digital platforms such as Instagram and other social networks for public health education. The study emphasizes the importance of targeted social media campaigns to improve stroke recognition, encourage timely medical response, and ultimately reduce stroke-related disability and mortality.

This study investigates the role of liver enzymes ALT (Alanine Aminotransferase) and AST (Aspartate Aminotransferase) as potential prognostic markers in patients with COVID-19 during the second wave of the pandemic in India. Clinical and laboratory data from 80 patients admitted to the Neuro ICU at Medanta Hospital, Lucknow, were analyzed to evaluate the relationship between ALT and AST levels and other biomarkers such as CRP, ferritin, and D-dimer.

The findings revealed that significantly elevated ALT and AST levels (>1000 U/L) were strongly associated with higher mortality among COVID-19 patients. The study highlights that these widely available and cost-effective biomarkers may serve as useful indicators for identifying high-risk patients and improving clinical decision-making during severe COVID-19 infections.

This cross-sectional observational study examined the etiological profile of optic neuropathy in patients admitted to the Neurology Department at Bangur Institute of Neurosciences (BIN), Kolkata. The research analyzed clinical presentation, biochemical findings, electrophysiological tests, and imaging characteristics in patients presenting with visual impairment and abnormal visual evoked potentials.

The study identified the most common causes of optic neuropathy, including idiopathic optic neuritis, tuberculosis-related optic neuropathy, multiple sclerosis, and anterior ischemic optic neuropathy. The findings provide valuable insights into the demographic distribution, clinical features, and underlying etiologies of optic neuropathy in a tertiary care setting, contributing to improved diagnostic evaluation and management strategies.

This randomized clinical trial investigated the impact of structured eye exercises on myopia in children aged 10–15 years. The study evaluated interventions such as palming, eye muscle warm-up exercises, cross-crawl movements, and Tibetan eye chart exercises over a three-week period. Outcomes were assessed using optical power measurements and the Convergence Insufficiency Symptom Survey (CISS) scale.

The findings demonstrated significant improvements in visual acuity and ocular health among participants performing the exercise regimen compared with the control group receiving standard care. The study highlights the potential role of targeted eye exercise programs as a non-invasive and cost-effective approach to support visual rehabilitation and help manage myopia progression in children.

This prospective randomized controlled study evaluated the clinical profile and outcomes of hyperglycemic patients admitted to the Intensive Care Unit (ICU). The research analyzed metabolic characteristics, treatment approaches, and clinical outcomes among critically ill patients receiving mechanical ventilation.

The study assessed the impact of intensive insulin therapy aimed at maintaining blood glucose levels between 80–110 mg/dL and compared outcomes with conventional treatment. Findings demonstrated that strict glycemic control significantly reduced morbidity and mortality among critically ill patients. The research also highlighted the prevalence of previously undiagnosed hyperglycemia in hospitalized patients and its association with longer ICU stays and poorer clinical outcomes.